Endocrine Abstracts

Background: Premature infants are at risk of delayed screening for congenital hypothyroidism (CH), which may markedly affect initial treatment time and neurodevelopmental outcome. Rescreening preterm infants at four weeks (30 days) of life has been recommended to detect cases with delayed TSH elevation.Aim: To examine the performance of the CH screening programme in preterm infants aged ≤32 weeks in terms of timing of the initial Guthrie tests, and...

Introduction: The prevalence of congenital malformations (CM) in congenital hypothyroidism (CH) is higher than expected, particularly for cardiac malformations, but the published data vary considerably – from 2.4% to 24% – in different series.Methods: Using existing databases for CH and Scottish population statistics, we have retrospectively determined the prevalence of cardiac, non–cardiac and syndromic disorders in Scotland since the int...

Introduction: Thyroid imaging is of proven help in establishing a diagnosis of congenital hypothyroidism in newly referred infants. Radio-isotope and/or ultrasound imaging is commonly used; each has weaknesses but have complimentary strengths and thus have been used in combination in our centre since 1999. We undertook a retrospective review and analysis of ultrasound imaging in infants with proven thyroid ectopia to re-examine the diagnoses.Patients and...